The school district can be thought of as analogous to the school districts of other cities and communities in the United States, but in some manners can also be thought of as analogous to the state education agencies of other states.
The district is headquartered at the Manuel F. L. Guerrero Administration Building at 312 Espinall Avenue, Hagåtña.
In 2000, 32,000 students attended Guam's Public School System. In 1998 the U.S. Department of Defense opened schools for children of American military personnel. DODEA schools had an attendance of 2,500 in 2000.
Around 2008, around one third of students graduating from the public schools on Guam go on to universities.
In the fall of 2008 the district required all schools to have school uniform policies for students. Any new schools opening must have policies in place after one year of the opening. Students eighteen years of age or older may opt out of the uniforms for medical, religious, or other reasons as approved by the building principal.
Adacao Elementary School (Mangilao
Agana Heights Elementary School (Agana Heights, opened 1958)
Astumbo Elementary School (Dededo, opened 1997)
B.P. Carbullido Elementary School (Barrigada, opened 1965)
Chief Brodie Memorial Elementary School (Tumon, Tamuning, opened 1965)
C.L. Taitano Elementary School (Sinajana, opened 1958)
Daniel L. Perez Elementary School (Yigo, opened 1968)
Formerly Yigo Elementary School (name changed in 1998)
F.Q. Sanchez Elementary School (Umatac, opened 1953)
Finegayan Elementary School (Dededo, opened 1972)
Harry S. Truman Elementary School (Santa Rita, opened 1966)
Inarajan Elementary School (Inarajan, opened 1953)
J.Q. San Miguel Elementary School (Mongmong-Toto-Maite, opened 1971)
Juan M. Guerrero Elementary School (Dededo, opened 1971)
Lyndon B. Johnson Elementary School (Tamuning, opened 1974)
Liguan Elementary School (Dededo, opened August 21, 2008)
Maria A. Ulloa Elementary School (Dededo, opened 1965)
Machananao Elementary School (Yigo, opened 1998)
Marcial Sablan Elementary School (Agat, opened 1998)
Merizo Martyrs Elementary School (Merizo, opened 1966)
Manuel Ulloa Lujan Elementary School (Yona, opened 1971)
Ordot/Chalan Pago Elementary School (Chalan-Pago-Ordot, opened 1997)
Pedro C. Lujan Elementary School (Barrigada, opened 1962)
Captain Henry B. Price Elementary School (Mangilao, opened 1958)
Talofofo Elementary School (Talofofo, opened 1965)
Tamuning Elementary School (Tamuning, opened 1965)
Upi Elementary School (Yigo, opened 1958)(Formerly Andersen Elementary until 1990)
Wettengel Elementary School (Dededo, opened 1968)
Astumbo Middle School (Dededo, opened on August 21, 2008)
Agueda Johnston Middle School (Chalan Pago-Ordot, opened 1966)
F.B. Leon Guerrero Middle School (Yigo, opened 1974)
Inarajan Middle School (Inarajan, opened 1973)
Jose Rios Middle School (Piti, opened 1973)
Luis P. Untalan Middle School (Barrigada, opened 1958)
Oceanview Middle School (Agat, opened 1959)
Originally Oceanview High School; became Oceanview Middle School in 1997.
Vicente S.A. Benavente Middle School (Dededo, opened 1966)
John F. Kennedy High School (Tumon, Tamuning, opened 1959)
Originally called Tumon High School
Okkodo High School (Dededo, opened on August 21, 2008)
Simon Sanchez High School (Yigo, opened 1974)
Founded as a junior high school in 1974, became a high school in 1981.
Southern High School (Santa Rita, opened 1997)
Tiyan High School (opened 2014)